Home

USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
Search by   *
 
 
 
 
 
 
Maps   
 
 


     Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     
Searching in 'USC-OGP 2-DE database' for entry matching: Q13148




USC-OGP 2-DE database:  Q13148


Q13148


General information about the entry
View entry in simple text format
Entry nameTADBP_HUMAN
Primary accession numberQ13148
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=TAR DNA-binding protein 43; Short=TDP-43;.
Gene nameName=TARDBP
Synonyms=TDP43
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=5.92; Mw=43904

Cross-references
UniProtKB/Swiss-ProtQ13148; TADBP_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameTADBP_HUMAN
Primary accession numberQ13148
Secondary accession number(s) A4GUK4 A4GUK5 A4GUK6 B2R629 B4DJ45 E2PU12 Q53H27 Q6FI92 Q96DJ0
Sequence was last modified on November 1, 1996 (version 1)
Annotations were last modified on March 15, 2017 (version 183)
Name and origin of the protein
DescriptionRecName: Full=TAR DNA-binding protein 43; Short=TDP-43;
Gene nameName=TARDBP
Synonyms=TDP43
Encoded onName=TARDBP; Synonyms=TDP43
Keywords3D-structure; Alternative splicing; Amyotrophic lateral sclerosis; Complete proteome; Direct protein sequencing; Disease mutation; DNA-binding; Isopeptide bond; Methylation; mRNA processing; mRNA splicing; Neurodegeneration; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; RNA-binding; Transcription; Transcription regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU23731; AAA70033.1; -; mRNA
EMBLEF434181; ABO32290.1; ALT_SEQ; mRNA
EMBLEF434182; ABO32291.1; -; mRNA
EMBLEF434183; ABO32292.1; ALT_SEQ; mRNA
EMBLAK295920; BAG58707.1; -; mRNA
EMBLAK312416; BAG35326.1; -; mRNA
EMBLCR533534; CAG38565.1; -; mRNA
EMBLAK222754; BAD96474.1; -; mRNA
EMBLAL050265; CAB43367.1; -; mRNA
EMBLAL109811; CAI22098.1; -; Genomic_DNA
EMBLCH471130; EAW71670.1; -; Genomic_DNA
EMBLBC071657; AAH71657.1; -; mRNA
EMBLBC095435; AAH95435.1; -; mRNA
CCDSCCDS122.1; -. [Q13148-1]; .
PIRI38977; I38977; .
RefSeqNP_031401.1; NM_007375.3. [Q13148-1]; .
RefSeqXP_016856352.1; XM_017000863.1. [Q13148-1]; .
RefSeqXP_016856353.1; XM_017000864.1. [Q13148-1]; .
RefSeqXP_016856354.1; XM_017000865.1. [Q13148-1]; .
RefSeqXP_016856355.1; XM_017000866.1. [Q13148-1]; .
RefSeqXP_016856356.1; XM_017000867.1. [Q13148-1]; .
RefSeqXP_016856357.1; XM_017000868.1. [Q13148-1]; .
UniGeneHs.300624; -; .
PDB1WF0; NMR; -; A=193-267
PDB2CQG; NMR; -; A=96-185
PDB2N2C; NMR; -; A=307-349
PDB2N3X; NMR; -; A=311-360
PDB2N4G; NMR; -; A=311-360
PDB2N4H; NMR; -; A=311-360
PDB2N4P; NMR; -; A=1-77
PDB4BS2; NMR; -; A=102-269
PDB4IUF; X-ray; 2.75 A; A=103-179
PDB4Y00; X-ray; 3.00 A; A/B/C/D=101-191
PDB4Y0F; X-ray; 2.65 A; A/B=101-191
PDBsum1WF0; -; .
PDBsum2CQG; -; .
PDBsum2N2C; -; .
PDBsum2N3X; -; .
PDBsum2N4G; -; .
PDBsum2N4H; -; .
PDBsum2N4P; -; .
PDBsum4BS2; -; .
PDBsum4IUF; -; .
PDBsum4Y00; -; .
PDBsum4Y0F; -; .
ProteinModelPortalQ13148; -; .
SMRQ13148; -; .
BioGrid117003; 330; .
DIPDIP-31167N; -; .
IntActQ13148; 36; .
MINTMINT-5002768; -; .
STRING9606.ENSP00000240185; -; .
ChEMBLCHEMBL2362981; -; .
iPTMnetQ13148; -; .
PhosphoSitePlusQ13148; -; .
SwissPalmQ13148; -; .
BioMutaTARDBP; -; .
DMDM20140568; -; .
EPDQ13148; -; .
MaxQBQ13148; -; .
PaxDbQ13148; -; .
PeptideAtlasQ13148; -; .
PRIDEQ13148; -; .
DNASU23435; -; .
EnsemblENST00000240185; ENSP00000240185; ENSG00000120948. [Q13148-1]; .
GeneID23435; -; .
KEGGhsa:23435; -; .
UCSCuc001art.4; human. [Q13148-1]; .
CTD23435; -; .
DisGeNET23435; -; .
GeneCardsTARDBP; -; .
GeneReviewsTARDBP; -; .
HGNCHGNC:11571; TARDBP; .
HPACAB003703; -; .
HPAHPA017284; -; .
MalaCardsTARDBP; -; .
MIM605078; gene; .
MIM612069; phenotype; .
neXtProtNX_Q13148; -; .
OpenTargetsENSG00000120948; -; .
Orphanet803; Amyotrophic lateral sclerosis; .
Orphanet275872; Frontotemporal dementia with motor neuron disease; .
PharmGKBPA36336; -; .
eggNOGENOG410IFJS; Eukaryota; .
eggNOGENOG410ZYQJ; LUCA; .
GeneTreeENSGT00850000132362; -; .
HOGENOMHOG000254792; -; .
HOVERGENHBG058671; -; .
InParanoidQ13148; -; .
OMAKHNSSRQ; -; .
OrthoDBEOG091G0BJZ; -; .
PhylomeDBQ13148; -; .
TreeFamTF315657; -; .
ChiTaRSTARDBP; human; .
EvolutionaryTraceQ13148; -; .
GeneWikiTARDBP; -; .
GenomeRNAi23435; -; .
PROPR:Q13148; -; .
ProteomesUP000005640; Chromosome 1; .
BgeeENSG00000120948; -; .
CleanExHS_TARDBP; -; .
ExpressionAtlasQ13148; baseline and differential; .
GenevisibleQ13148; HS; .
GOGO:0005737; C:cytoplasm; IEA:Ensembl; .
GOGO:0035061; C:interchromatin granule; IEA:Ensembl; .
GOGO:0016607; C:nuclear speck; IEA:Ensembl; .
GOGO:0005654; C:nucleoplasm; IDA:HPA; .
GOGO:0005634; C:nucleus; IDA:LIFEdb; .
GOGO:0005726; C:perichromatin fibrils; IEA:Ensembl; .
GOGO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL; .
GOGO:0042802; F:identical protein binding; IPI:IntAct; .
GOGO:0003730; F:mRNA 3'-UTR binding; IDA:BHF-UCL; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0003700; F:transcription factor activity; sequence-specific DNA binding; TAS:ProtInc
GOGO:0001205; F:transcriptional activator activity; RNA polymerase II distal enhancer sequence-specific binding; IEA:Ensembl
GOGO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:BHF-UCL; .
GOGO:0006397; P:mRNA processing; IEA:UniProtKB-KW; .
GOGO:0043922; P:negative regulation by host of viral transcription; IDA:BHF-UCL; .
GOGO:0010629; P:negative regulation of gene expression; IMP:CACAO; .
GOGO:0001933; P:negative regulation of protein phosphorylation; IMP:CACAO; .
GOGO:0030264; P:nuclear fragmentation involved in apoptotic nuclear change; IMP:CACAO; .
GOGO:0071765; P:nuclear inner membrane organization; IMP:CACAO; .
GOGO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl; .
GOGO:0051726; P:regulation of cell cycle; IMP:CACAO; .
GOGO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl; .
GOGO:0008380; P:RNA splicing; IDA:BHF-UCL; .
GOGO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc; .
Gene3D3.30.70.330; -; 2; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
PfamPF00076; RRM_1; 2; .
SMARTSM00360; RRM; 2; .
SUPFAMSSF54928; SSF54928; 2; .
PROSITEPS50102; RRM; 2; .



USC-OGP 2-DE database image


Gateways to other related servers


Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

[Home]